126775-74-4

126775-74-4 structure

Name: himastatin
Chemical Name: (5E,5'E,8E,8'E,19E,19'E)-3,3',5,5',8,8',17b,17b',19,19'-Decahydroxy-10,10'-bis(1-hydroxyethyl)-7,7'-diisobutyl-21,21',24,24'-tetraisopropyl-2,2',3,3',4,4',4a,4a',7,7',10,10',17b,17b',18,18',18a,18a',21,21'-icosahydro-12aH,12a'H-16,16'-bipyridazino[6'',1'':15',16'][1,4,7,10,13,16]oxapentaazacyclooctadecino[7',6':1,5]pyrrolo[2,3-b]indole-11,11',22,22',25,25'(1H,1'H,13H,13'H,24H,24'H)-hexone-(7E,20E,23E,39E,52E,55E)-4,7,17,20,23,36,39,49,52,55-decahydroxy-25,57-bis(1-hydroxyethyl)-22,54-diisobutyl-9,12,41,44-tetraisopropyl-11,43-dioxa-8,14,15,21,24,27,29,40,46,47,53,56,59,61-tetradecaazadecacyclo[31.31.0.03,62.04,60.06,59.014,19.027,38.028,36.030,35.046,51]tetrahexaconta-1(64),2,7,20,23,30,32,34,39,52,55,62-dodecaene-10,13,26,42,45,58-hexone (1:1)
CAS Number: 126775-74-4
Molecular Formula: C₁₄₄H₂₀₈N₂₈O₄₀
Molecular Weight: 2971.356
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2021-09-14 11:15:48
Modify Date: 2025-08-24 12:06:55
Himastatin is a antitumor antibiotic produced by a strain of S. hygroscopicus sp. Himastatin is a dimeric cyclohexadepsipeptide containing piperazic acid and a unique central aromatic core[1].

Name	(5E,5'E,8E,8'E,19E,19'E)-3,3',5,5',8,8',17b,17b',19,19'-Decahydroxy-10,10'-bis(1-hydroxyethyl)-7,7'-diisobutyl-21,21',24,24'-tetraisopropyl-2,2',3,3',4,4',4a,4a',7,7',10,10',17b,17b',18,18',18a,18a',21,21'-icosahydro-12aH,12a'H-16,16'-bipyridazino[6'',1'':15',16'][1,4,7,10,13,16]oxapentaazacyclooctadecino[7',6':1,5]pyrrolo[2,3-b]indole-11,11',22,22',25,25'(1H,1'H,13H,13'H,24H,24'H)-hexone-(7E,20E,23E,39E,52E,55E)-4,7,17,20,23,36,39,49,52,55-decahydroxy-25,57-bis(1-hydroxyethyl)-22,54-diisobutyl-9,12,41,44-tetraisopropyl-11,43-dioxa-8,14,15,21,24,27,29,40,46,47,53,56,59,61-tetradecaazadecacyclo[31.31.0.03,62.04,60.06,59.014,19.027,38.028,36.030,35.046,51]tetrahexaconta-1(64),2,7,20,23,30,32,34,39,52,55,62-dodecaene-10,13,26,42,45,58-hexone (1:1)

Description	Himastatin is a antitumor antibiotic produced by a strain of S. hygroscopicus sp. Himastatin is a dimeric cyclohexadepsipeptide containing piperazic acid and a unique central aromatic core[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Leet JE, Schroeder DR, Krishnan BS, Matson JA. Himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus. II. Isolation and characterization. J Antibiot (Tokyo). 1990;43(8):961-966.