55524-56-6

55524-56-6 structure

Name	motilin, Nle(13)-

Description	[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Motilin Receptor Research Areas >> Neurological Disease
In Vitro	[Nle13]-Motilin (0.1-30 nM, 15 min) increases the amplitude of electrically-evoked, neuronally-mediated contractions in the isolated gastric antrum[1]. [Nle13]-Motilin (0.3 μM, 10 min) induces a moderate increase in spontaneous contractility in the stomach[2].
References	[1]. Dass NB, et al. The rabbit motilin receptor: molecular characterisation and pharmacology. Br J Pharmacol. 2003 Nov;140(5):948-54. [2]. Venkova K, et al. Effect of TZP-201, a novel motilin receptor antagonist, in the colon of the musk shrew (Suncus murinus). J Pharm Pharmacol. 2009 Mar;61(3):367-73.

Molecular Formula	C₁₂₁H₁₉₀N₃₄O₃₅
Molecular Weight	2681.01