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1392499-33-0

1392499-33-0 structure
1392499-33-0 structure
  • Name: BocNH-PEG5-CH2CH2Br
  • Chemical Name: BocNH-PEG5-CH2CH2Br
  • CAS Number: 1392499-33-0
  • Molecular Formula: C17H34BrNO7
  • Molecular Weight: 444.36
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-07-27 14:33:42
  • Modify Date: 2024-01-13 15:36:30
  • BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name BocNH-PEG5-CH2CH2Br
Synonyms MFCD31580050
Description BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H34BrNO7
Molecular Weight 444.36
Hazard Codes Xi