DC Chemicals Limited
China
Product Name: Ac-hMCH(6–16)-NH2
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

1053601-50-5

1053601-50-5 structure

1053601-50-5 structure

Name: Ac-hMCH(6–16)-NH2
Chemical Name: Ac-hMCH(6–16)-NH2
CAS Number: 1053601-50-5
Molecular Formula: C₅₈H₉₉N₂₁O₁₃S₃
Molecular Weight: 1394.73
Catalog: Signaling Pathways GPCR/G Protein MCHR1 (GPR24)
Create Date: 2021-07-26 18:03:39
Modify Date: 2024-01-05 20:13:42
Ac-hMCH(6-16)-NH2 binds to and activates equally well both human MCH receptors present in the brain (non-selective agonist), with IC50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R[1].

Name	Ac-hMCH(6–16)-NH2

Description	Ac-hMCH(6-16)-NH2 binds to and activates equally well both human MCH receptors present in the brain (non-selective agonist), with IC50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> MCHR1 (GPR24) Research Areas >> Metabolic Disease
In Vitro	Ac-hMCH(6-16)-NH2 exhibits EC50 values of 20 nM and 98 nM for MCH-1R and MCH-2R in aequorin functional assay, respectively[1].
References	[1]. Maria A Bednarek, et al. Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1. J Biol Chem. 2002 Apr 19;277(16):13821-6.

Molecular Formula	C₅₈H₉₉N₂₁O₁₃S₃
Molecular Weight	1394.73