1346598-13-7

1346598-13-7 structure

Name: Esmolol-d7 (hydrochloride)
Chemical Name: Esmolol-d7 (hydrochloride)
CAS Number: 1346598-13-7
Molecular Formula: C₁₆H₁₉D₇ClNO₄
Molecular Weight: 338.878
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2021-06-14 09:41:53
Modify Date: 2024-01-10 17:24:00
Esmolol-d7 hydrochloride is the deuterium labeled Esmolol hydrochloride. Esmolol hydrochloride is a beta adrenergic receptor blocker[1][2].

Name	Esmolol-d7 (hydrochloride)
Synonyms	Benzenepropanoic acid, 4-[2-hydroxy-3-[[1-(methyl-d3)ethyl-1,2,2,2-d4]amino]propoxy]-, methyl ester, hydrochloride (1:1) Esmolol-d7 (hydrochloride) Methyl 3-(4-{2-hydroxy-3-[(2H7)-2-propanylamino]propoxy}phenyl)propanoate hydrochloride (1:1)

Description	Esmolol-d7 hydrochloride is the deuterium labeled Esmolol hydrochloride. Esmolol hydrochloride is a beta adrenergic receptor blocker[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Signaling Pathways >> Autophagy >> Mitophagy
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Wiest D. Esmolol. A review of its therapeutic efficacy and pharmacokinetic characteristics. Clin Pharmacokinet. 1995;28(3):190-202. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.