242143-80-2

242143-80-2 structure

Name: Tabimorelin hemifumarate
Chemical Name: Tabimorelin hemifumarate
CAS Number: 242143-80-2
Molecular Formula: C₆₈H₈₄N₈O₁₀
Molecular Weight: 1173.4
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2021-05-12 15:48:33
Modify Date: 2026-07-08 18:54:56
Tabimorelin (NN703) hemifumarate is an orally active growth hormone (GH) secretagogue. Tabimorelin hemifumarate is also a potent inhibitor of CYP3A4 activity[1].

Name	Tabimorelin hemifumarate
Synonyms	D-Phenylalaninamide, N-[(2E)-5-amino-5-methyl-1-oxo-2-hexen-1-yl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-, (2E)-2-butenedioate (2:1) N-[(2E)-5-Amino-5-methyl-2-hexenoyl]-N-methyl-3-(2-naphthyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamide (2E)-2-butenedioate (2:1) Tabimorelin N-[(2E)-5-Amino-5-methylhex-2-enoyl]-N-methyl-3-(2-naphthyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamide (2E)-but-2-enedioate (2:1)

Description	Tabimorelin (NN703) hemifumarate is an orally active growth hormone (GH) secretagogue. Tabimorelin hemifumarate is also a potent inhibitor of CYP3A4 activity[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Target	CYP3A4
References	[1]. Zdravkovic M, et al. A clinical study investigating the pharmacokinetic interaction between NN703 (tabimorelin), a potential inhibitor of CYP3A4 activity, and midazolam, a CYP3A4 substrate. Eur J Clin Pharmacol. 2003 Feb;58(10):683-8.