191931-56-3

191931-56-3 structure

Name: NTNCB hydrochloride
Chemical Name: NTNCB hydrochloride
CAS Number: 191931-56-3
Molecular Formula: C₂₅H₃₄ClN₃O₄S
Molecular Weight: 508.073
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2021-02-11 10:59:50
Modify Date: 2024-01-12 16:26:25
NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5[1].

Name	NTNCB hydrochloride
Synonyms	Benzenesulfonamide, 2-nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1) 2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride 2-Nitro-N-[(trans-4-{[(1,2,3,4-tetrahydro-2-naphthalenylmethyl)amino]methyl}cyclohexyl)methyl]benzenesulfonamide hydrochloride (1:1)

Description	NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	hY5 receptor:8 nM (Ki) hY1 receptor:16032 nM (Ki)
References	[1]. Islam I, et al. Discovery of potent and selective small molecule NPY Y5 receptor antagonists. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1767-9.