136186-07-7
136186-07-7 structure
- Name: TPC2-A1-N
- Chemical Name: TPC2-A1-N
- CAS Number: 136186-07-7
- Molecular Formula: C17H9Cl2F3N2O2
- Molecular Weight: 401.17
- Create Date: 2021-01-07 08:22:23
- Modify Date: 2025-08-25 16:26:27
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TPC2-A1-N is a novel, lipophilic, membrane permeable isoform-selective small molecule agonist of two-pore channel 2 (TPC2). TPC2-A1-N plays its role by mimicking the physiological actions of NAADP and PI(3,5)P2?through independent binding sites. TPC2-A1-N has inverse effects on key lysosomal activities and increases the pH in the lysosomal lumen in a TPC2-dependent manner.
| Name | TPC2-A1-N |
|---|
| Description | TPC2-A1-N is a novel, lipophilic, membrane permeable isoform-selective small molecule agonist of two-pore channel 2 (TPC2). TPC2-A1-N plays its role by mimicking the physiological actions of NAADP and PI(3,5)P2?through independent binding sites. TPC2-A1-N has inverse effects on key lysosomal activities and increases the pH in the lysosomal lumen in a TPC2-dependent manner. |
|---|
| Molecular Formula | C17H9Cl2F3N2O2 |
|---|---|
| Molecular Weight | 401.17 |