1820968-63-5

1820968-63-5 structure

Name: MSP3
Chemical Name: MSP-3
CAS Number: 1820968-63-5
Molecular Formula: C₁₆H₁₉NO₃S
Molecular Weight: 305.392
Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
Create Date: 2021-01-22 18:59:48
Modify Date: 2025-08-27 01:04:22
MSP-3 is a potent TRPV1 agonist, with an EC50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects[1].

Name	MSP-3
Synonyms	MSP-3 2-Thiophenebutanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]- N-(4-Hydroxy-3-methoxybenzyl)-4-(2-thienyl)butanamide N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide

Description	MSP-3 is a potent TRPV1 agonist, with an EC50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	TRPV1:0.87 μM (EC50)
References	[1]. Aiello F, et, al. Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. ACS Chem Neurosci. 2016 Jun 15;7(6):737-48.