16470-02-3
16470-02-3 structure
- Name: Epiblastin A
- Chemical Name: Epiblastin A
- CAS Number: 16470-02-3
- Molecular Formula: C12H10ClN7
- Molecular Weight: 287.708
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Casein Kinase
- Create Date: 2021-01-08 21:54:08
- Modify Date: 2025-08-25 23:13:21
-
Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1[1].
| Name | Epiblastin A |
|---|---|
| Synonyms |
MFCD02947161
6-(3-Chlorophenyl)-2,4,7-pteridinetriamine 6-(3-Chlorophenyl)pteridine-2,4,7-Triamine 2,4,7-Triamino-6-(m-chlorophenyl)-pteridine 2,4,7-Pteridinetriamine, 6-(3-chlorophenyl)- Epiblastin A |
| Description | Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 596.1±60.0 °C at 760 mmHg |
| Molecular Formula | C12H10ClN7 |
| Molecular Weight | 287.708 |
| Flash Point | 314.3±32.9 °C |
| Exact Mass | 287.068634 |
| LogP | 1.90 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.821 |
| Storage condition | -20°C |