1502027-70-4

1502027-70-4 structure

Name: ARN14988
Chemical Name: ARN14988
CAS Number: 1502027-70-4
Molecular Formula: C₁₆H₂₄ClN₃O₅
Molecular Weight: 373.832
Catalog: Research Areas Cancer
Create Date: 2021-01-07 19:47:19
Modify Date: 2025-11-29 16:32:35
ARN14988 is a potent inhibitor of acid ceramidase (ACDase) (IC50=12.8 nM for the human enzyme)[1].

Name	ARN14988
Synonyms	ARN14988 1(2H)-Pyrimidinecarboxylic acid, 5-chloro-3-[(hexylamino)carbonyl]-3,6-dihydro-2,6-dioxo-, 2-methylpropyl ester Isobutyl 5-chloro-3-(hexylcarbamoyl)-2,6-dioxo-3,6-dihydro-1(2H)-pyrimidinecarboxylate

Description	ARN14988 is a potent inhibitor of acid ceramidase (ACDase) (IC50=12.8 nM for the human enzyme)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Realini N, et al. Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. J Biol Chem. 2016 Jan 29;291(5):2422-34.