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2362575-45-7

2362575-45-7 structure
2362575-45-7 structure
  • Name: CRBN-6-5-5-VHL
  • Chemical Name: CRBN-6-5-5-VHL
  • CAS Number: 2362575-45-7
  • Molecular Formula: C51H69N7O10S
  • Molecular Weight: 972.20
  • Catalog: Signaling Pathways PROTAC PROTAC
  • Create Date: 2020-10-19 16:09:49
  • Modify Date: 2024-01-09 12:10:55
  • CRBN-6-5-5-VHL is a potent and selective cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3[1].

Name CRBN-6-5-5-VHL
Description CRBN-6-5-5-VHL is a potent and selective cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3[1].
Related Catalog
Target

Cereblon:1.5 nM (DC50)

References

[1]. Christian Steinebach, et al. PROTAC-mediated crosstalk between E3 ligases. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824.

Molecular Formula C51H69N7O10S
Molecular Weight 972.20
Hazard Codes Xi