886462-83-5

886462-83-5 structure

Name: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde trifluoroacetate salt
Chemical Name: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde trifluoroacetate salt
CAS Number: 886462-83-5
Molecular Formula: C₉₅H₁₆₂N₂₀O₂₆
Molecular Weight: 2000.421
Catalog: Signaling Pathways Apoptosis Caspase
Create Date: 2020-12-03 14:43:49
Modify Date: 2025-08-27 15:41:38
Caspase-8-IN-1 is a potent caspase-8 inhibitor[1].

Name	Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde trifluoroacetate salt
Synonyms	L-Alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-isoleucyl-N-[(2S,3R)-2-{acetyl[(2S)-1-carboxy-3-oxo-2-pr ;opanyl]amino}-3-hydroxybutanoyl]-L-α-glutamine L-α-Glutamine, L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-isoleucyl-N-[(2S,3R)-2-[acetyl[(1S)-2 -carboxy-1-formylethyl]amino]-3-hydroxy-1-oxobutyl]-

Description	Caspase-8-IN-1 is a potent caspase-8 inhibitor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Apoptosis >> Caspase
Target	Caspase-8
References	[1]. Joshi SG, et al. Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity. Infect Immun. 2003 Jul;71(7):4127-36.