183476-25-7

183476-25-7 structure

Name: Lactoferricin B (4-14) (bovine) trifluoroacetate salt
Chemical Name: Lactoferricin B (4-14) (bovine) trifluoroacetate salt
CAS Number: 183476-25-7
Molecular Formula: C₇₀H₁₁₃N₂₅O₁₃S
Molecular Weight: 1544.871
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2021-01-09 16:26:03
Modify Date: 2024-02-20 12:03:23
Lactoferricin, bovine is an iron-binding glycoprotein derived from the acidic hydrolysis of bovine lactoferrin. Lactoferricin, bovine has bactericidal, antifungal, antiparasitic, antitumor, antiviral, and immunomodulatory activities[1].

Name	Lactoferricin B (4-14) (bovine) trifluoroacetate salt
Synonyms	L-Arginyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-tryptophyl-L-arginyl-L-methionyl-L-lysyl-L-lysyl-L-leucylglycine Glycine, L-arginyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-tryptophyl-L-arginyl-L-methionyl-L-lysyl-L-lysyl-L-leucyl-

Description	Lactoferricin, bovine is an iron-binding glycoprotein derived from the acidic hydrolysis of bovine lactoferrin. Lactoferricin, bovine has bactericidal, antifungal, antiparasitic, antitumor, antiviral, and immunomodulatory activities[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Lactoferricin, bovine (50 or 100 μg/mL, 24 h) 在软骨细胞中以浓度依赖的方式显著降低 MMP-1、MMP-3 和 MMP-13 的 mRNA 和蛋白水平[1]。 Lactoferricin, bovine (50 μg/mL, 24 h) 可以有效激活 ERK MAPK 和 Akt 通路，从而介导抗炎作用[1]。
References	[1]. Dongyao Yan, et al. Bovine lactoferricin is anti-inflammatory and anti-catabolic in human articular cartilage and synovium. J Cell Physiol. 2013 Feb;228(2):447-56.