2229036-65-9
2229036-65-9 structure
- Name: TL 13-22
- Chemical Name: TL13-22
- CAS Number: 2229036-65-9
- Molecular Formula: C45H55ClN10O9S
- Molecular Weight: 947.50
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
- Create Date: 2020-08-10 19:11:47
- Modify Date: 2025-08-26 05:50:47
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TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells[1].
| Name | TL13-22 |
|---|
| Description | TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.54 nM (ALK)[1] |
| In Vitro | TL13-22 prompts the degradation of additional kinases including Aurora A, FER, PTK2, and RPS6KA1 with IC50 values of 11.3 nM, 5.74 nM, 18.4 nM, and 65.9 nM, respectively[1]. |
| References |
| Molecular Formula | C45H55ClN10O9S |
|---|---|
| Molecular Weight | 947.50 |