1306761-08-9

1306761-08-9 structure

1306761-08-9 structure

Name: RP101442
Chemical Name: RP101442
CAS Number: 1306761-08-9
Molecular Formula: C₂₃H₂₂N₄O₃
Molecular Weight: 402.45
Catalog: Signaling Pathways GPCR/G Protein LPL Receptor
Create Date: 2020-08-07 22:44:16
Modify Date: 2024-01-18 17:32:15
RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively[1].

Name	RP101442

Description	RP101442, an active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> LPL Receptor Research Areas >> Inflammation/Immunology
Target	S1PR1:2.6 nM (EC50) S1PR5:171 nM (EC50)
References	[1]. Tran JQ, et al. Cardiac Safety of Ozanimod, a Novel Sphingosine-1-Phosphate Receptor Modulator: Results of a Thorough QT/QTc Study. Clin Pharmacol Drug Dev. 2018;7(3):263-276.

Molecular Formula	C₂₃H₂₂N₄O₃
Molecular Weight	402.45