794466-43-6

794466-43-6 structure

Name: PBP 10
Chemical Name: PBP10
CAS Number: 794466-43-6
Molecular Formula: C₈₄H₁₂₇N₂₄O₁₅
Molecular Weight: 1713.06
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2020-08-11 18:05:03
Modify Date: 2024-01-16 18:27:08
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1[1]. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects[2].

Name	PBP10

Description	PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1[1]. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects[2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: formyl peptide receptor 2 (FPR2)[1]
References	[1]. C C Cunningham, et al.Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly. J Biol Chem [2]. Ewelina Piktel, et al. Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin. J Nanobiotechnology. 2019 Feb 2;17(1):22.

Molecular Formula	C₈₄H₁₂₇N₂₄O₁₅
Molecular Weight	1713.06