306959-01-3
306959-01-3 structure
- Name: MYLS22
- Chemical Name: MYLS22
- CAS Number: 306959-01-3
- Molecular Formula: C24H21N5O2S
- Molecular Weight: 443.52
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2020-08-11 17:52:06
- Modify Date: 2025-08-25 18:02:34
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MYLS22 is a first-in-class and selective optic atrophy 1 (OPA1) inhibitor. MYLS22 can target endothelial OPA1 to curtail tumor growth and inhibits angiogenesis by impinging on NFkB activity and on angiogenic gene expression[1].
| Name | MYLS22 |
|---|---|
| Synonyms | MFCD01062681 |
| Description | MYLS22 is a first-in-class and selective optic atrophy 1 (OPA1) inhibitor. MYLS22 can target endothelial OPA1 to curtail tumor growth and inhibits angiogenesis by impinging on NFkB activity and on angiogenic gene expression[1]. |
|---|---|
| Related Catalog | |
| Target |
OPA1[1] |
| In Vivo | MYLS22 (10 mg/kg/die; peritumoral injection; every 2 days for 14 days) causes the tumor growth curtailed mice[1]. Animal Model: 6-week-old C57BL6/J mice with B16F10 melanomas[1] Dosage: 10 mg/kg/die Administration: Peritumoral injection; every 2 days for 14 days Result: Caused the tumor growth curtailed. |
| References |
| Molecular Formula | C24H21N5O2S |
|---|---|
| Molecular Weight | 443.52 |
| Hazard Codes | Xi |
|---|