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256649-36-2

256649-36-2 structure
256649-36-2 structure
  • Name: CRA-2059
  • Chemical Name: CRA-2059
  • CAS Number: 256649-36-2
  • Molecular Formula: C34H46N12O8
  • Molecular Weight: 750.80
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
  • Create Date: 2020-08-07 18:39:55
  • Modify Date: 2024-01-10 22:31:07
  • CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
Name CRA-2059
Description CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
Related Catalog
In Vitro Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 has the potential for inflammatory bowel disease research[1].
References

[1]. Tremaine WJ, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Aliment Pharmacol Ther. 2002;16(3):407-413.

[2]. Selwood T, et al. Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor. Biol Chem. 2003;384(12):1605-1611.
Molecular Formula C34H46N12O8
Molecular Weight 750.80

Chemsrc provides CAS#:256649-36-2 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 256649-36-2 | Chemsrc address: https://www.chemsrc.com/en/baike/1566040.html

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