1438415-89-4

1438415-89-4 structure
1438415-89-4 structure
  • Name: TCO-PNB ester
  • Chemical Name: TCO-PNB ester
  • CAS Number: 1438415-89-4
  • Molecular Formula: C15H17NO5
  • Molecular Weight: 291.30
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:13:59
  • Modify Date: 2024-01-09 18:31:23
  • TCO-PNB ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name TCO-PNB ester
Description TCO-PNB ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H17NO5
Molecular Weight 291.30
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