2163772-19-6

2163772-19-6 structure

Name: 2-(3,6-Bis(dimethylamino)xanthylium-9-yl)-5-((2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)carbamoyl)benzoate
Chemical Name: TAMRA-PEG4-methyltetrazine
CAS Number: 2163772-19-6
Molecular Formula: C₄₂H₄₅N₇O₈
Molecular Weight: 775.85
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 10:10:55
Modify Date: 2024-01-05 12:15:48
TAMRA-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	TAMRA-PEG4-methyltetrazine
Synonyms	MFCD28385537

Description	TAMRA-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₂H₄₅N₇O₈
Molecular Weight	775.85