2107273-40-3

2107273-40-3 structure

2107273-40-3 structure

Name: N-(m-PEG4)-N'-(azide-PEG4)-Cy7
Chemical Name: N-(m-PEG4)-N'-(azide-PEG4)-Cy7
CAS Number: 2107273-40-3
Molecular Formula: C₄₆H₆₆ClN₅O₈
Molecular Weight: 852.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 00:48:01
Modify Date: 2024-01-02 16:02:21
N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(m-PEG4)-N'-(azide-PEG4)-Cy7

Description	N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₆H₆₆ClN₅O₈
Molecular Weight	852.50

Hazard Codes	Xi