2112731-46-9

2112731-46-9 structure

2112731-46-9 structure

Name: Methyltetrazine-amido-PEG7-azide
Chemical Name: Methyltetrazine-amido-PEG7-azide
CAS Number: 2112731-46-9
Molecular Formula: C₂₇H₄₂N₈O₈
Molecular Weight: 606.67
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 13:43:36
Modify Date: 2024-01-23 12:03:52
Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-amido-PEG7-azide

Description	Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₇H₄₂N₈O₈
Molecular Weight	606.67