2378590-46-4

2378590-46-4 structure

2378590-46-4 structure

Name: Fmoc-NH-PEG15-CH2CH2COOH
Chemical Name: Fmoc-NH-PEG15-CH2CH2COOH
CAS Number: 2378590-46-4
Molecular Formula: C₄₈H₇₇NO₁₉
Molecular Weight: 972.12
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 09:50:25
Modify Date: 2024-01-09 22:49:36
Fmoc-NH-PEG15-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Fmoc-NH-PEG15-CH2CH2COOH

Description	Fmoc-NH-PEG15-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₄₈H₇₇NO₁₉
Molecular Weight	972.12

Hazard Codes	Xi