2353409-50-2

2353409-50-2 structure

2353409-50-2 structure

Name: DBCO-PEG9-DBCO
Chemical Name: DBCO-PEG9-DBCO
CAS Number: 2353409-50-2
Molecular Formula: C₅₈H₇₀N₄O₁₃
Molecular Weight: 1031.20
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:23:17
Modify Date: 2024-01-14 10:08:50
DBCO-PEG9-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG9-DBCO

Description	DBCO-PEG9-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₅₈H₇₀N₄O₁₃
Molecular Weight	1031.20