2182601-79-0

2182601-79-0 structure

2182601-79-0 structure

Name: Bis(m-PEG4)-N-OH
Chemical Name: Bis(m-PEG4)-N-OH
CAS Number: 2182601-79-0
Molecular Formula: C₁₈H₃₉NO₉
Molecular Weight: 413.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:09:48
Modify Date: 2024-01-17 09:46:12
Bis(m-PEG4)-N-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis(m-PEG4)-N-OH

Description	Bis(m-PEG4)-N-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₃₉NO₉
Molecular Weight	413.50