2376111-92-9

2376111-92-9 structure

2376111-92-9 structure

Name: Amino-PEG7-acid
Chemical Name: Amino-PEG7-acid
CAS Number: 2376111-92-9
Molecular Formula: C₁₇H₃₅NO₉
Molecular Weight: 397.46
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 09:55:01
Modify Date: 2024-01-21 18:09:56
Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Amino-PEG7-acid

Description	Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₇H₃₅NO₉
Molecular Weight	397.46