2279944-67-9

2279944-67-9 structure

2279944-67-9 structure

Name: 2-Bromo-22-dimethyl-acetamido-PEG3-acid
Chemical Name: 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid
CAS Number: 2279944-67-9
Molecular Formula: C₁₃H₂₄BrNO₆
Molecular Weight: 370.24
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:13:30
Modify Date: 2023-04-09 22:56:19
2-Bromo-22-dimethyl-acetamido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-Bromo-2,2-dimethyl-acetamido-PEG3-acid

Description	2-Bromo-22-dimethyl-acetamido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₃H₂₄BrNO₆
Molecular Weight	370.24