1252676-55-3
1252676-55-3 structure
- Name: Waltonitone
- Chemical Name: Waltonitone
- CAS Number: 1252676-55-3
- Molecular Formula: C30H48O2
- Molecular Weight: 440.70
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2020-04-08 12:09:21
- Modify Date: 2024-01-21 18:29:27
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Waltonitone is a ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. Waltonitone significantly inhibits hepatocellular carcinoma cells growth and induces apoptosis in vitro and in vivo[1].
| Name | Waltonitone |
|---|
| Description | Waltonitone is a ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. Waltonitone significantly inhibits hepatocellular carcinoma cells growth and induces apoptosis in vitro and in vivo[1]. |
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| Related Catalog | |
| In Vitro | waltonitone (10 μM, 25 μM; for 48 hours) results in an increment of sub-G1 population in BEL-7402 cells[1]. Waltonitone (25 μM; for 48 hours) induces BEL-7402 cells apoptosis[1]. Waltonitone (25 μM; for 48 hours) can effectively activate caspase-3 in BEL-7402 cells[1]. |
| In Vivo | Waltonitone (i.v.; 20 mg/kg or 50 mg/kg; once every two days for 16 days) inhibits BEL-7402 tumor growth in male athymic mice (BALB/c nu/nu) in vivo[1]. |
| References |
| Molecular Formula | C30H48O2 |
|---|---|
| Molecular Weight | 440.70 |