850559-51-2

850559-51-2 structure

850559-51-2 structure

Name: BMVC2
Chemical Name: BMVC2
CAS Number: 850559-51-2
Molecular Formula: C₂₈H₂₅I₂N₃
Molecular Weight: 657.33
Catalog: Signaling Pathways Cell Cycle/DNA Damage G-quadruplex
Create Date: 2020-04-05 23:40:58
Modify Date: 2024-01-02 11:30:21
BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer[1].

Name	BMVC2

Description	BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> G-quadruplex
Target	G-quadruplex[1]
In Vitro	BMVC2 by monitoring the disappearance of the 291 nm CD signals of d[AG3(T2AG3)3] (HT22) after adding Cu2+ is screened, a longer unfolding time would dictate a better G4 stabilizer. The unfolding curve of HT22 in the presence of BMVC2 can be fitted by using two time constants of 133.7 s (29%) and 2816 s (71%), which are similar to the unfolding parameters of BMVC[1].
References	[1]. Jen-Fei Chu, et al. A Novel Method for Screening G-quadruplex Stabilizers to Human Telomeres. Journal of the Chinese Chemical Society, 2011, 58, 296-300.

Molecular Formula	C₂₈H₂₅I₂N₃
Molecular Weight	657.33