52250-38-1

52250-38-1 structure

Name: Violanone
Chemical Name: Violanone
CAS Number: 52250-38-1
Molecular Formula: C₁₇H₁₆O₆
Molecular Weight: 316.305
Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
Create Date: 2020-02-11 22:53:35
Modify Date: 2024-09-15 18:28:10
Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti[1][2].

Name	Violanone

Description	Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	Microtubule/Tubulin[1]
In Vitro	Violanone inhibitS the microtubule assembly by 16%[1]. Violanone shows larvicidal activity against A. aegypti, with an LC50 of 157.55 µg/mL[2].
References	[1]. Deesamer S, et, al. Synthesis and biological evaluation of isoflavone analogues from Dalbergia oliveri. Tetrahedron. 2007 Dec 24; 63(52): 12986-12993. [2]. Bezerra-Silva PC, et, al. Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito. Exp Parasitol. 2015 Jun;153:160-4.