1632484-77-5

1632484-77-5 structure

1632484-77-5 structure

Name: Ceritinib-d7
Chemical Name: Ceritinib D7
CAS Number: 1632484-77-5
Molecular Formula: C₂₈H₂₉D₇ClN₅O₃S
Molecular Weight: 565.18
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2020-01-23 11:17:51
Modify Date: 2024-01-22 21:38:45
Ceritinib D7 (LDK378 D7) is a deuterium labeled Ceritinib. Ceritinib is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor[1].

Name	Ceritinib D7

Description	Ceritinib D7 (LDK378 D7) is a deuterium labeled Ceritinib. Ceritinib is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Endocrinology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IGF-1R Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor
References	[1]. Marsilje TH, et al. Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials. J Med Chem. 2013 Jul 25;56(14):5675-90.

Molecular Formula	C₂₈H₂₉D₇ClN₅O₃S
Molecular Weight	565.18