2376724-97-7

2376724-97-7 structure

Name: Boc-C1-PEG3-C4-OH
Chemical Name: Boc-C1-PEG3-C4-OH
CAS Number: 2376724-97-7
Molecular Formula: C₁₆H₃₂O₆
Molecular Weight: 320.42
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-01-23 20:46:51
Modify Date: 2024-01-09 14:42:09
Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the alkyl chain composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	Boc-C1-PEG3-C4-OH

Description	Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the alkyl chain composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

Molecular Formula	C₁₆H₃₂O₆
Molecular Weight	320.42

Hazard Codes	Xi