413606-16-3
413606-16-3 structure
- Name: MitoBloCK-11
- Chemical Name: MitoBloCK-11
- CAS Number: 413606-16-3
- Molecular Formula: C17H12BrN3O4S
- Molecular Weight: 434.264
- Catalog: Research Areas Neurological Disease
- Create Date: 2020-01-19 22:20:56
- Modify Date: 2022-01-20 14:33:03
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MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
| Name | MitoBloCK-11 |
|---|
| Description | MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development. |
|---|---|
| References | References 1. Conti, M. (2018). Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy. UCLA. 2. Miyata N, et al. J Biol Chem. 2017 Mar 31;292(13):5429-5442. View Related Products by Target Other Targets |
| Molecular Formula | C17H12BrN3O4S |
|---|---|
| Molecular Weight | 434.264 |