2101739-18-6
2101739-18-6 structure
- Name: RAD51-IN-17
- Chemical Name: RAD51-IN-17
- CAS Number: 2101739-18-6
- Molecular Formula: C22H16ClN3O
- Molecular Weight: 373.84
- Catalog: Signaling Pathways Cell Cycle/DNA Damage RAD51
- Create Date: 2020-01-12 10:11:49
- Modify Date: 2023-01-29 12:04:54
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RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers.
| Name | RAD51-IN-17 |
|---|
| Description | RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers. |
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| References | References 1. Ward A, et al. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3096-3100. View Related Products by Target DNA Repair Protein |
| Molecular Formula | C22H16ClN3O |
|---|---|
| Molecular Weight | 373.84 |
| Storage condition | -20°C |