189109-89-5
189109-89-5 structure
- Name: SLV peptide
- Chemical Name: SLV peptide
- CAS Number: 189109-89-5
- Molecular Formula: C14H27N3O5
- Molecular Weight: 317.386
- Create Date: 2020-01-16 10:26:29
- Modify Date: 2024-01-16 09:14:52
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A tripeptide representing the Fas-C terminus that specifically blocks the interaction of Fap1 with Fas; increases apoptosis sensitivity and decreases β-catenin in vitro, also decrease interaction of Fap1 with Apc, does not alter expression of Fap1 or Apc proteins; induces Fas-mediated apoptosis in a colon cancer cell line that expresses both Fas and FAP-1.
| Name | SLV peptide |
|---|
| Description | A tripeptide representing the Fas-C terminus that specifically blocks the interaction of Fap1 with Fas; increases apoptosis sensitivity and decreases β-catenin in vitro, also decrease interaction of Fap1 with Apc, does not alter expression of Fap1 or Apc proteins; induces Fas-mediated apoptosis in a colon cancer cell line that expresses both Fas and FAP-1. |
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| References | References 1. Huang W, et al. Leukemia. 2016 Jul;30(7):1502-9. 2. Huang W, et al. J Biol Chem. 2013 May 3;288(18):12766-76. 3. Yanagisawa J, et al. J Biol Chem. 1997 Mar 28;272(13):8539-45. 4. Huang W, et al. Leuk Lymphoma. 2013 Mar;54(3):619-30. View Related Products by Target Fas Receptor |
| Molecular Formula | C14H27N3O5 |
|---|---|
| Molecular Weight | 317.386 |