1821669-43-5
1821669-43-5 structure
- Name: BRD2492
- Chemical Name: BRD2492
- CAS Number: 1821669-43-5
- Molecular Formula: C20H18N4O2
- Molecular Weight: 346.39
- Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
- Create Date: 2020-01-11 20:01:51
- Modify Date: 2025-03-26 12:09:01
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BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation.
| Name | BRD2492 |
|---|
| Description | BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation. |
|---|---|
| References | References 1. Wagner FF, et al. ACS Chem Biol. 2016 Feb 19;11(2):363-74. View Related Products by Target HDAC |
| Molecular Formula | C20H18N4O2 |
|---|---|
| Molecular Weight | 346.39 |