877969-69-2
877969-69-2 structure
- Name: VPC-80051(VPC80051)
- Chemical Name: VPC-80051
- CAS Number: 877969-69-2
- Molecular Formula: C16H13F2N3O
- Molecular Weight: 301.297
- Catalog: Research Areas Others
- Create Date: 2020-01-19 23:56:57
- Modify Date: 2024-01-21 07:20:20
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VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1; interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line, reduces AR-V7 mRNA levels.
| Name | VPC-80051 |
|---|
| Description | VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1; interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line, reduces AR-V7 mRNA levels. |
|---|---|
| References | References 1. Carabet LA, et al. Molecules. 2019 Feb 20;24(4). pii: E763. View Related Products by Target Spliceosome |
| Molecular Formula | C16H13F2N3O |
|---|---|
| Molecular Weight | 301.297 |