2082762-29-4
2082762-29-4 structure
- Name: KGP-420
- Chemical Name: KGP-420
- CAS Number: 2082762-29-4
- Molecular Formula: C14H13BrN3Na2O4PS
- Molecular Weight: 476.192
- Create Date: 2020-01-20 19:18:56
- Modify Date: 2023-09-07 09:39:14
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KGP-420 is the water-soluble phosphate prodrug of KGP-94 in vivo studies, KGP-94 is a potent, selective cathepsin L inhibitor with IC50 of 189 nM; readily converts to KGP-94, and shows cytotoxicity against HUVECs with GI50 of 20.2 uM.
| Name | KGP-420 |
|---|
| Description | KGP-420 is the water-soluble phosphate prodrug of KGP-94 in vivo studies, KGP-94 is a potent, selective cathepsin L inhibitor with IC50 of 189 nM; readily converts to KGP-94, and shows cytotoxicity against HUVECs with GI50 of 20.2 uM. |
|---|---|
| References | References 1. Parker EN, et al. Bioorg Med Chem Lett. 2017 Mar 1;27(5):1304-1310. View Related Products by Target Cathepsin |
| Molecular Formula | C14H13BrN3Na2O4PS |
|---|---|
| Molecular Weight | 476.192 |