1443448-82-5
1443448-82-5 structure
- Name: SEMBL
- Chemical Name: SEMBL
- CAS Number: 1443448-82-5
- Molecular Formula: C12H11NO4
- Molecular Weight: 233.223
- Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
- Create Date: 2020-01-20 00:34:56
- Modify Date: 2024-04-11 10:35:55
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SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65; inhibits LPS-induced NF-κB activation, iNOS expression, and inflammatory cytokine secretions; also inhibits NF-κB and cellular invasion in ovarian carcinoma ES-2 cells; enhances stability in aqueous solution compared with (-)-DHMEQ.
| Name | SEMBL |
|---|
| Description | SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65; inhibits LPS-induced NF-κB activation, iNOS expression, and inflammatory cytokine secretions; also inhibits NF-κB and cellular invasion in ovarian carcinoma ES-2 cells; enhances stability in aqueous solution compared with (-)-DHMEQ. |
|---|---|
| References | References 1. Sidthipong K, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):562-566. View Related Products by Target NF-κB |
| Molecular Formula | C12H11NO4 |
|---|---|
| Molecular Weight | 233.223 |