Name | MK-9470 |
---|---|
Synonyms |
MK-9470
N-[(2S,3S)-3-(3-Cyanophenyl)-4-(4-ethoxyphenyl)-2-butanyl]-2-methyl-2-[(5-methyl-2-pyridinyl)oxy]propanamide Propanamide, N-[(1S,2S)-2-(3-cyanophenyl)-3-(4-ethoxyphenyl)-1-methylpropyl]-2-methyl-2-[(5-methyl-2-pyridinyl)oxy]- |
Description | MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM, 18F MK-9470 has been developed for use in human brain imaging. |
---|---|
References | References 1. Burns HD, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9800-5. 2. Van Laere K, et al. J Nucl Med. 2008 Mar;49(3):439-45. 3. Gérard N, et al. J Mol Neurosci. 2010 Oct;42(2):162-7. View Related Products by Target Cannabinoid Receptor |
Density | 1.2±0.1 g/cm3 |
---|---|
Boiling Point | 656.3±55.0 °C at 760 mmHg |
Molecular Formula | C29H33N3O3 |
Molecular Weight | 471.591 |
Flash Point | 350.7±31.5 °C |
Exact Mass | 471.252197 |
LogP | 5.78 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.585 |