1432043-31-6

1432043-31-6 structure

Name: WAY 267464 dihydrochloride
Chemical Name: 4-(3,5-Dihydroxybenzyl)-N-{2-methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-1-piperazinecarboxamide dihydrochloride
CAS Number: 1432043-31-6
Molecular Formula: C₃₂H₃₇Cl₂N₇O₄
Molecular Weight: 654.587
Create Date: 2020-01-11 19:38:26
Modify Date: 2025-09-19 11:51:42
WAY-267464 (WAY267464) is a potent, selective, non-peptide oxytocin receptor agonist with Ki of 58.4 nM, >100-fold selectivity over V1a, V2, V1b receptors; exhibits an anxiolytic-like profile similar to oxytocin (OT), also significantly reverses disruption in prepulse inhibition of the acoustic startle reflex induced by either MK-801 or amphetamine in vivo.

Name	4-(3,5-Dihydroxybenzyl)-N-{2-methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-1-piperazinecarboxamide dihydrochloride
Synonyms	4-(3,5-Dihydroxybenzyl)-N-{2-methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-1-piperazinecarboxamide dihydrochloride 1-Piperazinecarboxamide, N-[[4-[(4,10-dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-, hydrochloride (1:2)

Description	WAY-267464 (WAY267464) is a potent, selective, non-peptide oxytocin receptor agonist with Ki of 58.4 nM, >100-fold selectivity over V1a, V2, V1b receptors; exhibits an anxiolytic-like profile similar to oxytocin (OT), also significantly reverses disruption in prepulse inhibition of the acoustic startle reflex induced by either MK-801 or amphetamine in vivo.
References	References 1. Ring RH, et al. Neuropharmacology. 2010 Jan;58(1):69-77. 2. Hicks C, et al. J Neuroendocrinol. 2012 Jul;24(7):1012-29. 3. Hicks C, et al. Br J Pharmacol. 2014 Jun;171(11):2868-87. 4. Hicks C, et al. Psychopharmacology (Berl). 2015 Aug;232(15):2659-67. View Related Products by Target Oxytocin Receptor (OXTR)