944252-63-5

944252-63-5 structure

Name: Murepavadin (POL7080)
Chemical Name: murepavadin
CAS Number: 944252-63-5
Molecular Formula: C₇₃H₁₁₂N₂₂O₁₆
Molecular Weight: 1553.808
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2020-01-11 20:52:51
Modify Date: 2025-08-24 21:27:16
Murepavadin (POL7080) is a highly potent, specific, macrocycle Pseudomonas antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Bacterial Infection Phase 3 Clinical

Name	murepavadin
Synonyms	1H,5H-Dipyrrolo[1,2-a:1',2'-d][1,4,7,10,13,16,19,22,25,28,31,34,37,40]tetradecaazacyclodotetracontine-5,10,13,16,19,22,25,28,31,34,37,40,43,46(46aH)-tetradecone, 17,20,26,29,35-pentakis(2-aminoethyl)-32-(3-aminopropyl)triacontahydro-44-[(1R)-1-hydroxyethyl]-11-(hydroxymethyl)-23,41-bis(1H-indol-3-ylmethyl)-14-methyl-38-[(1S)-1-methylpropyl]-, (5aR,11S,14S,17S,20S,23S,26S,29R,32S,35S,38S,41S,44S,46aS)- 10070 (5aR,11S,14S,17S,20S,23S,26S,29R,32S,35S,38S,41S,44S,46aS)-17,20,26,29,35-Pentakis(2-aminoethyl)-32-(3-aminopropyl)-38-[(2S)-2-butanyl]-44-[(1R)-1-hydroxyethyl]-11-(hydroxymethyl)-23,41-bis(1H-indol-3-ylmethyl)-14-methyltriacontahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d][1,4,7,10,13,16,19,22,25,28,31,34,37,40]tetradecaazacyclodotetracontine-5,10,13,16,19,22,25,28,31,34,37,40,43,46(46aH)-tetradecone murepavadin

Description	Murepavadin (POL7080) is a highly potent, specific, macrocycle Pseudomonas antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Bacterial Infection Phase 3 Clinical
References	References 1. Bassetti M, et al. Curr Opin Infect Dis. 2018 Jan 13. doi: 10.1097/QCO.0000000000000438. View Related Products by Target Bacterial Bacterial Infection