596108-59-7

596108-59-7 structure

Name: Aminopeptidase N Inhibitor
Chemical Name: [3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid
CAS Number: 596108-59-7
Molecular Formula: C₁₇H₁₀N₂O₈
Molecular Weight: 370.270
Create Date: 2020-01-11 14:23:34
Modify Date: 2025-08-20 11:36:24
Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).

Name	[3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid
Synonyms	3-nitro-2-(2-nitrophenyl)-4-oxo-4H-1-benzopyran-8-acetic acid [3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid 4H-1-Benzopyran-8-acetic acid, 3-nitro-2-(2-nitrophenyl)-4-oxo-

Description	Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).
In Vitro	Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), ��-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 ��M.