2088135-12-8
2088135-12-8 structure
- Name: SR 16832
- Chemical Name: 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
- CAS Number: 2088135-12-8
- Molecular Formula: C17H12ClN3O4
- Molecular Weight: 357.748
- Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
- Create Date: 2020-01-11 21:59:49
- Modify Date: 2024-01-02 19:39:34
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SR 16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone; a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ.
| Name | 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide |
|---|---|
| Synonyms |
2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
Benzamide, 2-chloro-N-(6-methoxy-4-quinolinyl)-5-nitro- |
| Description | SR 16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone; a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ. |
|---|---|
| References | References 1. Brust R, et al. ACS Chem Biol. 2017 Apr 21;12(4):969-978. View Related Products by Target PPAR |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 492.3±45.0 °C at 760 mmHg |
| Molecular Formula | C17H12ClN3O4 |
| Molecular Weight | 357.748 |
| Flash Point | 251.5±28.7 °C |
| Exact Mass | 357.051636 |
| LogP | 3.70 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.708 |