1883548-88-6
1883548-88-6 structure
- Name: FFN 206 dihydrochloride
- Chemical Name: 4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one dihydrochloride
- CAS Number: 1883548-88-6
- Molecular Formula: C12H16Cl2N2O2
- Molecular Weight: 291.174
- Catalog: Research Areas Others
- Create Date: 2020-01-12 16:08:48
- Modify Date: 2024-04-08 19:12:48
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FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles; the apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine; an useful tool for optical examination of VMAT2 function in cell culture.
| Name | 4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one dihydrochloride |
|---|---|
| Synonyms |
4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one dihydrochloride
2H-1-Benzopyran-2-one, 4-(2-aminoethyl)-7-(methylamino)-, hydrochloride (1:2) |
| Description | FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles; the apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine; an useful tool for optical examination of VMAT2 function in cell culture. |
|---|---|
| References | References 1. Hu G, et al. ACS Chem Biol. 2013 Sep 20;8(9):1947-54. View Related Products by Target Monoamine Transporter |
| Molecular Formula | C12H16Cl2N2O2 |
|---|---|
| Molecular Weight | 291.174 |
| Exact Mass | 290.058868 |