1807453-83-3
1807453-83-3 structure
- Name: ND-336
- Chemical Name: 1-(4-{4-[(2-Thiiranylmethyl)sulfonyl]phenoxy}phenyl)methanamine hydrochloride (1:1)
- CAS Number: 1807453-83-3
- Molecular Formula: C16H17NO3S2•HCl
- Molecular Weight: 371.902
- Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
- Create Date: 2020-01-11 16:26:50
- Modify Date: 2024-01-05 23:45:27
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A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively; has minimal effect on other MMPs; accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thereby reversing the pathological condition.
| Name | 1-(4-{4-[(2-Thiiranylmethyl)sulfonyl]phenoxy}phenyl)methanamine hydrochloride (1:1) |
|---|---|
| Synonyms |
1-(4-{4-[(2-Thiiranylmethyl)sulfonyl]phenoxy}phenyl)methanamine hydrochloride (1:1)
Benzenemethanamine, 4-[4-[(thiiranylmethyl)sulfonyl]phenoxy]-, hydrochloride (1:1) |
| Description | A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively; has minimal effect on other MMPs; accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thereby reversing the pathological condition. |
|---|---|
| References | References 1. Gao M, et al. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15226-31. View Related Products by Target Matrix Metalloproteinase (MMP) |
| Molecular Formula | C16H17NO3S2•HCl |
|---|---|
| Molecular Weight | 371.902 |
| Exact Mass | 371.041656 |
| Storage condition | 2-8°C |