1431935-92-0
1431935-92-0 structure
- Name: Volixibat potassium
- Chemical Name: volixibat potassium
- CAS Number: 1431935-92-0
- Molecular Formula: C38H50KN3O12S2
- Molecular Weight: 844.045
- Create Date: 2020-01-11 21:40:49
- Modify Date: 2024-01-21 11:32:07
-
A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH). Steatohepatitis Phase 2 Clinical
| Name | volixibat potassium |
|---|---|
| Synonyms |
YWU8J6O8J0
volixibat potassium Potassium 3-O-benzyl-N-({3-[(3S,4R,5R)-3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxido-2,3,4,5-tetrahydro-1-benzothiepin-5-yl]phenyl}carbamoyl)-6-O-sulfonato-β-D-glucopyranosylamine β-D-Glucopyranosylamine, N-[[[3-[(3S,4R,5R)-3-butyl-7-(dimethylamino)-3-ethyl-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenyl]amino]carbonyl]-3-O-(phenylmethyl)-, 6-(hydrogen su lfate), potassium salt (1:1) LUM002 UNII:YWU8J6O8J0 |
| Description | A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH). Steatohepatitis Phase 2 Clinical |
|---|---|
| References | References 1. Siebers N, et al. Eur J Drug Metab Pharmacokinet. 2017 Jul 12. doi: 10.1007/s13318-017-0429-7. 2. Tiessen RG, et al. BMC Gastroenterol. 2018 Jan 5;18(1):3. View Related Products by Target ASBT Transporter (SLC10A2) Steatohepatitis |
| Molecular Formula | C38H50KN3O12S2 |
|---|---|
| Molecular Weight | 844.045 |
| Exact Mass | 843.247314 |