1332879-51-2
1332879-51-2 structure
- Name: Pitstop 1
- Chemical Name: Sodium 2-(4-aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonate
- CAS Number: 1332879-51-2
- Molecular Formula: C19H13N2NaO5S
- Molecular Weight: 404.372
- Create Date: 2020-01-12 09:38:51
- Modify Date: 2025-08-27 18:56:30
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A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation); inhibits endocytic recycling of synaptic vesicles in neurons and in situ.
| Name | Sodium 2-(4-aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonate |
|---|---|
| Synonyms |
Sodium 2-(4-aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonate
1H-Benz[de]isoquinoline-5-sulfonic acid, 2-[(4-aminophenyl)methyl]-2,3-dihydro-1,3-dioxo-, sodium salt (1:1) |
| Description | A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation); inhibits endocytic recycling of synaptic vesicles in neurons and in situ. |
|---|---|
| References | References 1. von Kleist L, et al. Cell. 2011 Aug 5;146(3):471-84. 2. Nilewski LG, et al. ACS Chem Neurosci. 2017 Aug 14. doi: 10.1021/acschemneuro.7b00138. View Related Products by Target Clathrin |
| Molecular Formula | C19H13N2NaO5S |
|---|---|
| Molecular Weight | 404.372 |
| Exact Mass | 404.044281 |