900498-44-4

900498-44-4 structure

Name: Peimisine hydrochloride
Chemical Name: Peimisine hydrochloride
CAS Number: 900498-44-4
Molecular Formula: C₂₇H₄₂ClNO₃
Molecular Weight: 464.080
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2019-12-19 15:01:48
Modify Date: 2025-08-26 07:22:20
Peimisine (Ebeiensine) hydrochloride non-competitively antagonizes tracheal smooth muscle muscarinic M receptor and inhibits smooth muscle contraction caused by Ach. Peimisine hydrochloride excits β-receptor, restrains the release of internal calcium, and promotes to releaseing NO in order to relax tracheal smooth muscle and relieve asthma[1].

Name	Peimisine hydrochloride
Synonyms	Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-5(6H)-one, 1,2,3,3'a,4,4',4a,5',6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, (3S,3'R,3a'S,4aS,6'S,6aR,6bS,7a'R,9R,11aS,11bR)-, hydrochloride (1:1) (3β,5α,22S,23R)-3-Hydroxy-5,6-dihydro-17,23-epoxyveratraman-6-one hydrochloride (1:1)

Description	Peimisine (Ebeiensine) hydrochloride non-competitively antagonizes tracheal smooth muscle muscarinic M receptor and inhibits smooth muscle contraction caused by Ach. Peimisine hydrochloride excits β-receptor, restrains the release of internal calcium, and promotes to releaseing NO in order to relax tracheal smooth muscle and relieve asthma[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Inflammation/Immunology
References	[1]. Pan F, et al. Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis. Phytomedicine. 2014 Jul-Aug;21(8-9):1104-9.